SCHEMBL366711

SCHEMBL366711

CCOC([O])c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
POLB P06746 2/20 0.44
TAAR1 Q96RJ0 3/20 0.41
LMNA P02545 2/20 0.41
MMP8 P22894 1/20 0.41
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
HTT P42858 2/20 0.39
ATM Q13315 1/20 0.39
SCN1A P35498 2/20 0.38
SCN2A Q99250 2/20 0.38
SCN3A Q9NY46 2/20 0.38
GLA P06280 1/20 0.38
CYP1A2 P05177 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
ADRA2A P08913 1/20 0.38
CYP2D6 P10635 1/20 0.38
CHRM1 P11229 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9642930 0.83 LMNA (0.41) POLBLMNAHTTSCN1ASCN2A
SCHEMBL6588121 0.79 LTA4H (0.44) L3MBTL1LMNAPPARGPPARACYP1A2
SCHEMBL1040114 0.79 CES2 (0.38) TAAR1LMNAHTTSCN1ASCN2A
SCHEMBL9662373 0.78 TSHR (0.41) L3MBTL1LMNAHTTATMSCN1A
SCHEMBL1703020 0.78 LMNA (0.47) LMNACHRM2ADRA2ATSHROPRK1
SCHEMBL2178101 0.77 DPP4 (0.44) L3MBTL1POLBTAAR1LMNAADRA2A
SCHEMBL7563457 0.77 L3MBTL1 (0.42) L3MBTL1POLBTAAR1LMNAMMP8
SCHEMBL7053897 0.77 TSHR (0.39) TAAR1LMNAHTTSCN1ASCN2A
SCHEMBL7662943 0.77 CES2 (0.37) TAAR1LMNAHTTSCN1ASCN2A
SCHEMBL28184748 0.77 L3MBTL1 (0.43) L3MBTL1POLBLMNAMMP8PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012007008-A1 INHIBITORS OF HDME EPITHERAPEUTICS APS (DK) 2012-01-19 WO claimed
US-4116241-A FOR CONTROLLED ORAL ADMINISTRATION OF DRUG ALZA CORPORATION (US) 1978-09-26 US claimed
CN-117866200-A Polybenzoxazole precursor, process for producing the same, and photosensitive resin composition 上海交通大学 2024-04-12 CN disclosed
CN-113518792-B Polybenzoxazole precursor containing ester diamine, photosensitive resin composition, dry film, cured product, and electronic component 太阳控股株式会社 2023-08-15 CN disclosed
CN-113518792-A Polybenzoxazole precursor containing ester diamine, photosensitive resin composition, dry film, cured product, and electronic component 太阳控股株式会社 2021-10-19 CN disclosed
CN-112449688-A Photosensitive resin composition, dry film, cured product, and electronic component 太阳控股株式会社 2021-03-05 CN disclosed
US-9263767-B2 Electrolyte solution for electrochemical devices WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2016-02-16 US disclosed
US-20140162143-A1 ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICES WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2014-06-12 US disclosed
EP-2738862-A1 ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICES Wako Pure Chemical Industries, Ltd. (JP) 2014-06-04 EP disclosed
WO-2012007008-A1 INHIBITORS OF HDME EPITHERAPEUTICS APS (DK) 2012-01-19 WO disclosed
US-20110281040-A1 LIQUID CRYSTAL DISPLAY ELEMENT, POSITIVE TYPE RADIATION SENSITIVE COMPOSITION, INTERLAYER INSULATING FILM FOR LIQUID CRYSTAL DISPLAY ELEMENT, AND FORMATION METHOD THEREOF JSR CORPORATION (JP) 2011-11-17 US disclosed
US-4533730-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1985-08-06 US disclosed
EP-0055444-B1 TRISUBSTITUTED PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1985-03-20 EP disclosed
US-4504659-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1985-03-12 US disclosed
US-4478833-A ANTICOAGULANTS DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-10-23 US disclosed
US-4478997-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1984-10-23 US disclosed
US-4443598-A ANTIBIOTICS AND INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1984-04-17 US disclosed
US-4366316-A FROM OXAZOLINOAZETIDINONE AND ACID SHIONOGI & CO., LTD. (JP) 1982-12-28 US disclosed
EP-0055444-A2 Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them Dr. Karl Thomae GmbH (DE) 1982-07-07 EP disclosed
US-4203982-A Arylmalonamidomethoxycephalosporins SHIONOGI & CO., LTD. (JP) 1980-05-20 US disclosed