Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28913999 | 0.90 | POLB (0.57) | POLBTAAR1PKMMAPK1ALDH1A1 | |
| SCHEMBL9544841 | 0.83 | POLB (1.00) | POLBPKMMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL12869177 | 0.80 | POLB (0.61) | POLBALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL17228373 | 0.74 | POLB (0.59) | POLBALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL12869192 | 0.74 | POLB (0.83) | POLBMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL9433553 | 0.73 | L3MBTL1 (0.47) | TAAR1PKMMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL19296900 | 0.73 | LMNA (0.67) | POLBMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL8321902 | 0.73 | POLB (0.81) | POLBMAPK1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL9609548 | 0.73 | POLB (0.51) | POLBMAPK1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2033213 | 0.70 | MT-CO2 (0.69) | POLBMAPK1ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307429-A1 | PROCESS FOR ASYMMETRIC SYNTHESIS OF SUBSTITUTED 1,4-DIHYDROPYRIDINES | AstraZeneca AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| EP-1307420-A1 | PROCESS FOR SYNTHESIS OF $g(a),$g(b)-UNSATURATED KETONES | AstraZeneca AB (SE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002010134-A1 | PROCESS FOR ASYMMETRIC SYNTHESIS OF SUBSTITUTED 1,4-DIHYDROPYRIDINES | ASTRAZENECA AB (SE) | 2002-02-07 | — | — | WO | disclosed |
| WO-2002010103-A1 | PROCESS FOR SYNTHESIS OF α,β-UNSATURATED KETONES | ASTRAZENECA AB (SE) | 2002-02-07 | — | — | WO | disclosed |