Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LIG1 | P18858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460830 | 1.00 | ALDH1A1 (0.60) | ALDH1A1GLATDP1TSHRCYP3A4 | |
| SCHEMBL31384189 | 1.00 | ALDH1A1 (0.60) | ALDH1A1GLATDP1TSHRCYP3A4 | |
| SCHEMBL7519381 | 1.00 | ALDH1A1 (0.60) | ALDH1A1GLATDP1TSHRCYP3A4 | |
| SCHEMBL22357196 | 0.86 | ALDH1A1 (0.78) | ALDH1A1GLATDP1TSHRCYP3A4 | |
| SCHEMBL679937 | 0.86 | ALDH1A1 (0.78) | ALDH1A1GLATDP1TSHRCYP3A4 | |
| SCHEMBL9630670 | 0.84 | ALDH1A1 (0.57) | ALDH1A1GLATDP1TSHRCYP3A4 | |
| SCHEMBL7315191 | 0.82 | ALDH1A1 (0.51) | ALDH1A1GLATDP1TSHRCYP3A4 | |
| SCHEMBL5957095 | 0.82 | TSHR (0.48) | ALDH1A1GLATSHRCYP3A4TP53 | |
| SCHEMBL5957092 | 0.82 | TSHR (0.48) | ALDH1A1GLATSHRCYP3A4TP53 | |
| SCHEMBL6632887 | 0.81 | TDP1 (0.43) | ALDH1A1GLATDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103013945-A | Epoxide hydrolase mutant as well as gene and application of epoxide hydrolase mutant | UNIV EAST CHINA SCIENCE & TECH | 2013-04-03 | — | — | CN | claimed |
| US-20200216752-A1 | HYDROXYL-FUNCTIONAL UNSATURATED POLYAMINE SILICONE LIGAND SUITABLE FOR QUANTUM DOT COMPOSITIONS AND ARTICLES | 3M INNOVATIVE PROPERTIES COMPANY | 2020-07-09 | — | — | US | disclosed |
| CN-103013945-B | Epoxide hydrolase mutant as well as gene and application of epoxide hydrolase mutant | UNIV EAST CHINA SCIENCE & TECH | 2014-06-11 | — | — | CN | disclosed |
| CN-103013945-A | Epoxide hydrolase mutant as well as gene and application of epoxide hydrolase mutant | UNIV EAST CHINA SCIENCE & TECH | 2013-04-03 | — | — | CN | disclosed |
| US-20090042895-A1 | Antidepressant Piperidine Derivatives of Heterocycle-Fused Benzodioxans | WYETH (US) | 2009-02-12 | — | — | US | disclosed |
| US-20090042874-A1 | ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | WYETH (US) | 2009-02-12 | — | — | US | disclosed |
| US-7479500-B2 | Antidepressant piperidine derivatives of heterocyclefused benzodioxans | WYETH (US) | 2009-01-20 | — | — | US | disclosed |
| US-7419986-B2 | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans | WYETH (US) | 2008-09-02 | — | — | US | disclosed |
| US-7335666-B2 | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans | WYETH (US) | 2008-02-26 | — | — | US | disclosed |
| US-20070004702-A1 | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans | WYETH (US) | 2007-01-04 | — | — | US | disclosed |
| EP-0026298-A1 | Method for promoting growth and reducing fat in animals using phenylethanolamine derivatives | AMERICAN CYANAMID COMPANY (US) | 1981-04-08 | — | — | EP | disclosed |
| EP-0004532-A1 | 1-Aryloxy-3-nitratoalkylamino-2-propanols, process for their preparation and pharmaceutical compositions | MERCK PATENT GmbH (DE) | 1979-10-17 | — | — | EP | disclosed |
| US-4139623-A | HYPOTENSIVE AGENTS | C-G CORP. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4075335-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-4075208-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-4029795-A | 4(2' Isoquinolin-1-one)piperidines | CIBA-GEIGY CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |
| US-4027027-A | BETA-RECEPTOR-BLOCKERS, HYPOTENSIVES AND VALODILATORS; FOR TREATING ARRYTHMIAS AND ANGINA PECTORIS | CIBA-GEIGY CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
| US-4018778-A | ADRENALYTIC OR ANTIARRYTHMIC AGENTS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-04-19 | — | — | US | disclosed |
| US-3969512-A | N,N'bis-(3-phenoxy-2-hydroxy-propyl)-alkylenediamines and salts thereof | BOEHRINGER INGELHEIM GMBH (DT) | 1976-07-13 | — | — | US | disclosed |
| US-3956335-A | HYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042874-A1 | ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | HTR5A, CRH, CYP17A1 | ALDH1A1 643/4885GLA 3960/4885TDP1 1284/4885 |
| US-20070004702-A1 | Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans | CRH, CYP19A1, HTR5A | ALDH1A1 640/4885GLA 3214/4885TDP1 678/4885 |
| US-20090042895-A1 | Antidepressant Piperidine Derivatives of Heterocycle-Fused Benzodioxans | HTR5A, OPRD1, CRH | ALDH1A1 394/4885GLA 4241/4885TDP1 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.