Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053828 | 0.69 | NTRK1 (0.45) | ALDH1A1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL14108716 | 0.69 | MAPT (0.38) | CHRM2CHRM1CHRM3SLC6A2SLC6A4 | |
| SCHEMBL6971447 | 0.66 | SLC6A2 (0.41) | CHRM2CHRM1CHRM3SLC6A2SLC6A4 | |
| SCHEMBL3811128 | 0.64 | NR1H4 (0.49) | CPB1NR1H4 | |
| SCHEMBL6959626 | 0.64 | OPRM1 (0.41) | DRD4DRD3CHRM2CHRM1CHRM3 | |
| SCHEMBL934534 | 0.64 | PTGDR2 (0.52) | MMP13ALDH1A1 | |
| SCHEMBL6971033 | 0.64 | NR3C1 (0.42) | DRD4DRD3DRD2NR3C1ALDH1A1 | |
| SCHEMBL3811131 | 0.64 | NR1H4 (0.49) | CPB1NR1H4ALDH1A1 | |
| SCHEMBL6966662 | 0.64 | NPSR1 (0.44) | NR3C1ALDH1A1 | |
| SCHEMBL3811557 | 0.63 | CPB1 (0.49) | CPB1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |