Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960286 | 0.87 | NR3C1 (0.38) | NR3C1MEP1AMEP1BPDK1CACNA2D1 | |
| SCHEMBL6966037 | 0.80 | ALKBH1 (0.43) | MEP1AMEP1BNOTUMTSPOPDK1 | |
| SCHEMBL6966662 | 0.80 | NPSR1 (0.44) | NR3C1MEP1AMEP1BNOTUMTSPO | |
| SCHEMBL6973143 | 0.80 | MAPK1 (0.42) | NR3C1MEP1AMEP1BNOTUMHTR6 | |
| SCHEMBL15357022 | 0.74 | TSPO (0.42) | HTR6TSPOALDH1A1NPSR1MEN1 | |
| SCHEMBL6969995 | 0.72 | ACP1 (0.45) | DRD2DRD4DRD3ALDH1A1HSD17B10 | |
| SCHEMBL29331970 | 0.72 | NOTUM (0.57) | NOTUMALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL6971350 | 0.71 | MEP1A (0.44) | NR3C1MEP1AMEP1BTSPOPDK1 | |
| SCHEMBL6970219 | 0.70 | MEP1A (0.41) | NR3C1MEP1AMEP1BNOTUMPDK1 | |
| SCHEMBL6972391 | 0.70 | MEP1A (0.39) | MEP1AMEP1BNOTUMPDK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |