SCHEMBL7056883

SCHEMBL7056883

O=C(CCCCCCCCCCCCCCCCC(c1ccccc1)c1ccccc1)O[SiH3]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.52
HTR2A P28223 3/20 0.43
HRH1 P35367 3/20 0.43
GRM2 Q14416 1/20 0.42
GRM3 Q14832 1/20 0.42
TBXA2R P21731 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC10 Q969S8 2/20 0.41
HDAC11 Q96DB2 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 2/20 0.41
HDAC9 Q9UKV0 2/20 0.41
HDAC5 Q9UQL6 2/20 0.41
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7057732 1.00 TBXAS1 (0.52) TBXAS1HTR2AHRH1GRM2GRM3
SCHEMBL27946531 1.00 TBXAS1 (0.52) TBXAS1HTR2AHRH1GRM2GRM3
SCHEMBL707771 0.93 HRH1 (0.46) TBXAS1HTR2AHRH1GRM2GRM3
SCHEMBL705573 0.90 MTNR1A (0.44) TBXAS1HTR2AHRH1GRM2GRM3
SCHEMBL28556129 0.81 LMNA (0.51) TBXAS1HTR2AHRH1SIGMAR1MTNR1A
SCHEMBL7683666 0.80 TBXAS1 (0.73) TBXAS1HTR2AHRH1GRM2GRM3
SCHEMBL7773626 0.80 TBXAS1 (0.73) TBXAS1HTR2AHRH1GRM2GRM3
SCHEMBL28533624 0.79 TBXAS1 (0.58) TBXAS1HTR2AHRH1GRM2GRM3
SCHEMBL7773234 0.79 TBXAS1 (0.58) TBXAS1HTR2AHRH1GRM2GRM3
SCHEMBL27194866 0.78 TBXAS1 (0.58) TBXAS1TBXA2RHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed