Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5083378 | 0.72 | RAB9A (0.39) | RAB9AMAPTL3MBTL1LMNAMEN1 | |
| SCHEMBL3484026 | 0.63 | RAB9A (0.66) | RAB9AMAPTALDH1A1TP53GAA | |
| SCHEMBL3997292 | 0.61 | ALDH1A1 (0.43) | RAB9AMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL6420225 | 0.60 | ALDH1A1 (0.58) | RAB9AALDH1A1GAAHTTNPSR1 | |
| SCHEMBL19974868 | 0.60 | PAX8 (0.45) | RAB9AMAPTALDH1A1L3MBTL1HTT | |
| SCHEMBL10939224 | 0.59 | TSHR (0.57) | RAB9AMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL7256502 | 0.59 | POLB (0.45) | ALDH1A1TP53L3MBTL1HTTNPSR1 | |
| SCHEMBL27598322 | 0.59 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1HTTNPSR1KMT2A | |
| SCHEMBL29229966 | 0.59 | MAPT (0.57) | RAB9AMAPTALDH1A1TP53GAA | |
| SCHEMBL13374189 | 0.59 | L3MBTL1 (0.61) | RAB9AMAPTALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429807-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA Pharma AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003024489-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA PHARMA AG (DE) | 2003-03-27 | — | — | WO | disclosed |