Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057318 | 0.87 | CCR3 (0.54) | SLC5A7CCR3DRD2DRD3CCR2 | |
| SCHEMBL7050625 | 0.85 | DRD2 (0.54) | SLC5A7CCR3DRD2DRD3CCR2 | |
| SCHEMBL7052223 | 0.81 | DRD3 (0.77) | DRD2DRD3DRD4ALDH1A1 | |
| SCHEMBL7055667 | 0.77 | CCR3 (0.49) | CCR3DRD2DRD3CCR2MEN1 | |
| SCHEMBL12437365 | 0.76 | MEN1 (0.61) | SLC5A7CCR3DRD2DRD3MEN1 | |
| SCHEMBL6396595 | 0.76 | CCR3 (0.70) | CCR3MEN1KMT2ARAB9AOPRM1 | |
| SCHEMBL17194340 | 0.75 | OPRM1 (0.66) | SLC5A7CCR3MEN1KMT2ANPC1 | |
| SCHEMBL14026961 | 0.73 | SLC5A7 (0.54) | SLC5A7MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL14006003 | 0.73 | TSHR (0.70) | DRD2DRD3CCR2DRD4TSHR | |
| SCHEMBL18871751 | 0.73 | OPRK1 (0.69) | OPRK1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |