Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 7/20 | 0.65 |
| ▸ | TUBB | P07437 | 7/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.65 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.65 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.65 |
| ▸ | IKBKB | O14920 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055446 | 0.85 | IKBKB (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7053757 | 0.81 | PTPN1 (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7052936 | 0.74 | IKBKB (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7055593 | 0.74 | MAPT (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7055165 | 0.73 | CHEK1 (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10052108 | 0.72 | IKBKB (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4097204 | 0.72 | IKBKB (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19029351 | 0.71 | HDAC6 (0.83) | HDAC6 | |
| SCHEMBL5195941 | 0.71 | KDM4E (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7056469 | 0.70 | IKBKB (0.79) | IKBKBMAPTPTPN1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028731-A1 | CHK1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |