Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.52 |
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051897 | 0.85 | DRD2 (0.69) | RAB9AMEN1POLBKMT2AHDAC3 | |
| SCHEMBL7057796 | 0.80 | DRD3 (0.71) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7119593 | 0.80 | CCR3 (0.55) | DRD2CCR2DRD3CCR3 | |
| Hydrochloric Acid SCHEMBL7056135 | 0.79 | DRD4 (0.59) | DRD2HTR1AHTR2ACCR2DRD3 | |
| SCHEMBL7054406 | 0.78 | DRD3 (0.57) | DRD2HTR1AHTR2ADRD3HTR2C | |
| SCHEMBL7055659 | 0.77 | DRD2 (0.50) | DRD2CCR2DRD3CCR3 | |
| SCHEMBL7052435 | 0.76 | DRD2 (0.48) | DRD2HTR1AHTR2ACCR2DRD3 | |
| SCHEMBL7052427 | 0.76 | DRD2 (0.48) | POLBDRD2HTR1AHTR2ACCR2 | |
| SCHEMBL7057584 | 0.76 | DRD3 (0.69) | DRD2DRD3 | |
| SCHEMBL7060979 | 0.76 | DRD2 (0.52) | MEN1KMT2ADRD2CCR2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |