SCHEMBL7058633

SCHEMBL7058633

CS(=O)(=O)N(Cc1ccc(O)cc1)S(C)(=O)=O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.45
APLNR P35414 1/20 0.43
ESR1 P03372 7/20 0.41
ESR2 Q92731 3/20 0.41
TAS2R14 Q9NYV8 3/20 0.41
ALDH1A1 P00352 1/20 0.41
ALDH2 P05091 1/20 0.41
MTOR P42345 1/20 0.40
BLM P54132 1/20 0.39
CA2 P00918 1/20 0.39
CAMK2A Q9UQM7 1/20 0.39
ABAT P80404 1/20 0.38
MGLL Q99685 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4624980 0.79 MAPT (0.44) APLNRALDH1A1CA2
SCHEMBL4667161 0.79 ESR1 (0.53) ESR1ESR2ALDH1A1
SCHEMBL2492170 0.78 TSHR (0.53) ALDH1A1CA2
SCHEMBL20207280 0.73 APLNR (0.84) APLNRESR2TAS2R14
SCHEMBL27503924 0.72 ESR1 (0.54) APLNRESR1ALDH1A1CA2MGLL
SCHEMBL7169489 0.72 ALOX15 (0.43) APLNRALDH1A1CA2
SCHEMBL29217460 0.71 ENPP2 (0.50) ENPP2ESR1ESR2ALDH1A1CA2
SCHEMBL31201812 0.71 ESR1 (0.65) ESR1ALDH1A1
SCHEMBL9416592 0.70 BCHE (0.53) ESR1ESR2ALDH1A1ALDH2MTOR
SCHEMBL116611 0.70 HRH3 (0.64) ESR1ESR2ALDH1A1ALDH2MTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1425328-A1 FAST-SETTING 1K-POLYURETHANE GLUE Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-09 EP disclosed
WO-2003016368-A1 FAST-SETTING 1K-POLYURETHANE GLUE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-02-27 WO disclosed
WO-2002009863-A2 MICROCAPSULE, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF IN ADHESIVES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-02-07 WO disclosed
WO-1999048942-A9 POLYURETHANE AND PREPARATION CONTAINING POLYURETHANE HENKEL KGAA (DE) 2001-03-22 WO disclosed