SCHEMBL70607

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL691908	0.78	TSHR (0.52)	CYP3A4MAPK1TSHRHPGDHSD17B10
	SCHEMBL11151784	0.78	MAPK1 (0.48)	CYP3A4MAPK1TSHRHPGDHSD17B10
	SCHEMBL29238999	0.78	CYP3A4 (0.48)	CYP3A4MAPK1TSHRHPGDHSD17B10
	SCHEMBL31392414	0.78	CYP3A4 (0.75)	CYP3A4MAPK1TSHRHPGDHSD17B10
	SCHEMBL68064	0.78	CYP3A4 (0.75)	CYP3A4MAPK1TSHRHPGDHSD17B10
	SCHEMBL7743436	0.78	CYP3A4 (0.75)	CYP3A4MAPK1TSHRHPGDHSD17B10
	SCHEMBL28902325	0.72	ALOX15 (0.31)	HPGDHSP90AA1NR1I2LMNATTR
	SCHEMBL9623381	0.72	MEN1 (0.50)	CYP3A4MAPK1ESR1ESR2
	SCHEMBL5180281	0.72	TTR (0.49)	CYP3A4MAPK1TSHRHSD17B10TTR
	SCHEMBL11119604	0.69	CYP3A4 (0.89)	CYP3A4MAPK1TSHRHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.