Thioglycolic Acid

Thioglycolic Acid

SCHEMBL7061183

O=C(O)CS.O=C1CCC(=O)N1O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ACE P12821 4/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
LMNA P02545 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mercaptopropionic Acid SCHEMBL29219444 0.85 ACE (0.41) TSHRACEALDH1A1PKMKMT2A
Succinic Acid SCHEMBL28916613 0.83 LMNA (0.45) TSHRCA12CA1CA9ALDH1A1
Succinic Acid SCHEMBL722926 0.83 LMNA (0.45) TSHRCA12CA1CA9ALDH1A1
Bicarbonate SCHEMBL6150295 0.82 CA1 (0.38) TSHRCA12CA1CA9ALDH1A1
Bicarbonate SCHEMBL14917 0.82 CA1 (0.38) TSHRCA12CA1CA9ALDH1A1
Chloroacetic Acid SCHEMBL23933668 0.81 TSHR (0.48) TSHRCA12CA1CA9ALDH1A1
Glycine SCHEMBL1681950 0.81 GLRA1 (0.48) TSHRCA12CA1CA9ALDH1A1
Propionic Acid SCHEMBL1518988 0.81 FFAR3 (0.48) TSHRCA12CA1CA9ALDH1A1
Bromoacetic Acid SCHEMBL1064789 0.81 TSHR (0.48) TSHRCA12CA1CA9ALDH1A1
Oxalic Acid SCHEMBL9728851 0.79 CA12 (0.37) CA12CA1CA9ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484706-A Immunoassay for analytes in samples using alkylating agents PASTEUR SANOFI DIAGNOSTICS (FR) 1996-01-16 US claimed
WO-2003036297-A1 NON-IMMUNOLOGICAL ASSAYS FOR THE DETECTION AND DETERMINATION OF C-REACTIVE PROTEIN TRIDELTA DEVELOPMENT LIMITED (IE) 2003-05-01 WO disclosed
US-5484706-A Immunoassay for analytes in samples using alkylating agents PASTEUR SANOFI DIAGNOSTICS (FR) 1996-01-16 US disclosed