SCHEMBL7063309

SCHEMBL7063309

C[C@H](C(C(N)=O)c1ccc(F)cc1)N(C)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)COCC(C)(C)NC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 7/20 0.38
TACR1 P25103 2/20 0.33
MC4R P32245 1/20 0.33
MC3R P41968 1/20 0.33
MC1R Q01726 1/20 0.33
CASR P41180 1/20 0.33
MMP9 P14780 2/20 0.32
FCER2 P06734 1/20 0.32
MME P08473 1/20 0.32
ACE P12821 1/20 0.32
MMP8 P22894 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6317857 0.92 CTSB (0.36) GHSRTACR1MMP9FCER2MMP8
SCHEMBL7063301 0.84 GHSR (0.42) GHSRTACR1MC4RMC3RMC1R
SCHEMBL7063312 0.84 GHSR (0.39) GHSRTACR1MC4RMC3RMC1R
SCHEMBL6318994 0.78 GHSR (0.46) GHSRMC4RMC3RCASRMMP9
SCHEMBL6325175 0.78 GHSR (0.46) GHSRMC4RMC3RCASRMMP9
SCHEMBL7065310 0.77 GHSR (0.43) GHSRTACR1
SCHEMBL6317853 0.77 CTSS (0.37) GHSRTACR1MMP9FCER2MMP8
SCHEMBL6317848 0.76 CTSS (0.40) GHSRMC4RMC3RMC1RFCER2
SCHEMBL6324898 0.75 GHSR (0.40) GHSRMC4RMC3RMC1R
SCHEMBL7065306 0.75 GHSR (0.42) GHSRTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030055261-A1 Compounds with growth hormone releasing properties HELSINN THERAPEUTICS (U.S.), INC. 2003-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055261-A1 Compounds with growth hormone releasing properties GHRHR, GHSR, IGFBP1 GHSR 2/4885TACR1 241/4885MC4R 105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.