Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.33 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417398 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPTCYP3A4HSD17B10PLIN1 | |
| SCHEMBL252445 | 0.78 | LPAR3 (0.50) | ALDH1A1CYP3A4HSD17B10LPAR2LPAR3 | |
| SCHEMBL11696767 | 0.78 | LPAR3 (0.41) | LPAR2LPAR3 | |
| SCHEMBL8997333 | 0.78 | ALDH1A1 (0.57) | ALDH1A1CYP3A4HSD17B10LPAR2LPAR3 | |
| SCHEMBL28355615 | 0.77 | LPAR3 (0.53) | ALDH1A1CYP3A4HSD17B10LPAR2LPAR3 | |
| SCHEMBL5015029 | 0.77 | LPAR3 (0.44) | ALDH1A1CYP3A4HSD17B10LPAR2LPAR3 | |
| SCHEMBL1050408 | 0.77 | LPAR3 (0.53) | ALDH1A1CYP3A4HSD17B10LPAR2LPAR3 | |
| SCHEMBL28359216 | 0.77 | LPAR3 (0.53) | ALDH1A1CYP3A4HSD17B10LPAR2LPAR3 | |
| SCHEMBL1050405 | 0.77 | LPAR3 (0.53) | ALDH1A1CYP3A4HSD17B10LPAR2LPAR3 | |
| SCHEMBL28359116 | 0.77 | LPAR3 (0.53) | ALDH1A1CYP3A4HSD17B10LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593263-B1 | Lubricants, greases, aqueous fluids and concentrates containing additives derived from dimercaptothiadiazoles | LUBRIZOL CORP (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-0580335-B1 | Grease compositions | LUBRIZOL CORP (US) | 1997-09-10 | — | — | EP | disclosed |
| EP-0580331-B1 | Grease compositions | LUBRIZOL CORP (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5362409-A | Thiophosphorus acid ester | THE LUBRIZOL CORPORATION (US) | 1994-11-08 | — | — | US | disclosed |
| US-5318712-A | Reacted with A,B-unsaturated ester; antiwear, antioxidant | THE LUBRIZOL CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0593263-A1 | Lubricants, greases, aqueous fluids and concentrates containing additives derived from dimercaptothiadiazoles | The Lubrizol Corporation (US) | 1994-04-20 | — | — | EP | disclosed |
| EP-0580335-A1 | Grease compositions | The Lubrizol Corporation (US) | 1994-01-26 | — | — | EP | disclosed |
| EP-0580331-A1 | Grease compositions | The Lubrizol Corporation (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5256320-A | Overbased metal salts, thiophosphates, and phosphites blended | THE LUBRIZOL CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |
| US-5256321-A | Grease compositions | THE LUBRIZOL CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |