Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293930 | 0.82 | HCAR2 (0.38) | TDP1ABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL23336184 | 0.81 | TDP1 (0.34) | TDP1CYP4F2CYP4A11 | |
| SCHEMBL28973659 | 0.79 | ATM (0.47) | TDP1CYP1A2TSHRCYP4F2CYP4A11 | |
| SCHEMBL23336302 | 0.78 | CA12 (0.36) | TDP1 | |
| SCHEMBL8990561 | 0.78 | ABCB11 (0.33) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL3441150 | 0.78 | PKM (0.46) | TDP1ABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL23336298 | 0.77 | NAAA (0.47) | TSHR | |
| SCHEMBL28973635 | 0.75 | ADORA3 (0.35) | TDP1CYP3A4TSHRPPARACYP4F2 | |
| SCHEMBL23336299 | 0.75 | PTPN1 (0.32) | TDP1CYP3A4CYP4F2CYP4A11 | |
| SCHEMBL3910492 | 0.74 | POLB (0.43) | TDP1CYP1A2CYP3A4CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-11-20 | — | — | US | disclosed |
| US-6586368-B1 | Benzofuran derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | CBR3, CBR1, HAAO | TDP1 1151/4885ABCB11 3953/4885CYP1A2 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.