SCHEMBL7064327

SCHEMBL7064327

CCCCCCCCOC(=O)C(CCOS(C)(=O)=O)OS(C)(=O)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.41
TSHR P16473 4/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
MMP9 P14780 1/20 0.40
ALOX15 P16050 1/20 0.40
EPHX1 P07099 1/20 0.39
CA1 P00915 8/20 0.38
CA2 P00918 8/20 0.38
CA9 Q16790 7/20 0.38
CA12 O43570 3/20 0.38
CA7 P43166 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066614 0.94 ALDH1A1 (0.39) NAAATSHRKDM4EUSP2ALDH1A1
SCHEMBL7971358 0.93 TSHR (0.43) NAAATSHRKDM4EUSP2ALDH1A1
SCHEMBL7973307 0.93 TSHR (0.43) NAAATSHRKDM4EUSP2ALDH1A1
SCHEMBL7971310 0.88 TSHR (0.44) NAAATSHRKDM4EUSP2ALDH1A1
SCHEMBL7969892 0.87 ALDH1A1 (0.41) NAAATSHRKDM4EUSP2ALDH1A1
SCHEMBL7065794 0.83 ALDH1A1 (0.38) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL7976055 0.79 KDM4E (0.47) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL7066030 0.78 ALDH1A1 (0.39) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL9294187 0.77 NAAA (0.44) NAAATSHRALDH1A1LMNAEPHX1
SCHEMBL9295260 0.77 NAAA (0.44) NAAATSHRALDH1A1LMNAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed