Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 14/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064334 | 0.88 | FKBP1A (0.48) | FKBP1A | |
| SCHEMBL7062870 | 0.87 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7067220 | 0.87 | KDM4E (0.54) | — | |
| SCHEMBL7066527 | 0.86 | FKBP1A (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7066622 | 0.85 | CHRM3 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6236413 | 0.83 | OPRM1 (0.44) | FKBP1A | |
| SCHEMBL6234263 | 0.83 | OPRM1 (0.44) | FKBP1A | |
| SCHEMBL2770397 | 0.83 | OPRM1 (0.44) | FKBP1A | |
| SCHEMBL7067172 | 0.81 | OPRM1 (0.43) | FKBP1A | |
| SCHEMBL7065791 | 0.81 | OPRM1 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |