Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067220 | 0.89 | KDM4E (0.54) | KDM4ENPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL7064328 | 0.88 | CHRM2 (0.46) | FKBP1A | |
| SCHEMBL7068090 | 0.86 | ALDH1A1 (0.44) | KDM4ESMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL4669567 | 0.86 | FKBP1A (0.50) | FKBP1APREPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7064400 | 0.85 | FKBP1A (0.50) | FKBP1APREPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6236413 | 0.85 | OPRM1 (0.44) | FKBP1AKDM4ETSHROPRM1OPRD1 | |
| SCHEMBL2770397 | 0.85 | OPRM1 (0.44) | FKBP1AKDM4ETSHROPRM1OPRD1 | |
| SCHEMBL6234263 | 0.85 | OPRM1 (0.44) | FKBP1AKDM4ETSHROPRM1OPRD1 | |
| SCHEMBL7062870 | 0.84 | CHRM2 (0.43) | FKBP1AKDM4ETSHROPRM1OPRD1 | |
| SCHEMBL7065791 | 0.82 | OPRM1 (0.43) | KDM4ESMN1; SMN2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |