SCHEMBL7066622

SCHEMBL7066622

CCCCCCCCOC(=O)C1CCN1C(CC)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 9/20 0.47
CHRM2 P08172 8/20 0.47
CHRM4 P08173 8/20 0.47
CHRM5 P08912 8/20 0.47
CHRM1 P11229 8/20 0.47
PPARG P37231 3/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 2/20 0.43
TSHR P16473 1/20 0.42
ALDH1A1 P00352 1/20 0.42
FKBP1A P62942 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7062870 0.95 CHRM2 (0.43) CHRM3CHRM2CHRM4CHRM5CHRM1
SCHEMBL7060882 0.87 CHRM2 (0.47) CHRM3CHRM2CHRM4CHRM5CHRM1
SCHEMBL7067220 0.86 KDM4E (0.54) NPC1RAB9ASMN1; SMN2TSHRALDH1A1
SCHEMBL7064328 0.85 CHRM2 (0.46) CHRM3CHRM2CHRM4CHRM5CHRM1
SCHEMBL7064334 0.82 FKBP1A (0.48) NPC1RAB9ASMN1; SMN2TSHRFKBP1A
SCHEMBL7064527 0.82 CHRM2 (0.44) CHRM3CHRM2CHRM4CHRM5CHRM1
SCHEMBL6236413 0.82 OPRM1 (0.44) LMNATSHRALDH1A1FKBP1AKDM4E
SCHEMBL2770397 0.82 OPRM1 (0.44) LMNATSHRALDH1A1FKBP1AKDM4E
SCHEMBL6234263 0.82 OPRM1 (0.44) LMNATSHRALDH1A1FKBP1AKDM4E
SCHEMBL7067172 0.80 OPRM1 (0.43) NPC1RAB9ASMN1; SMN2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827954-B1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL CO (JP) 2003-06-04 EP disclosed
US-6114543-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-09-05 US disclosed
US-5880291-A Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-09 US disclosed
EP-0827954-A1 Process for producing optically active azetidine-2-carboxylic acid SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-03-11 EP disclosed