Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31055812 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL2945200 | 0.84 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL28532626 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL621720 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL635539 | 0.80 | PTGS1 (0.52) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL5208343 | 0.80 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL14399033 | 0.79 | ALDH1A1 (0.73) | KDM4EALDH1A1HSD17B10LMNASMN1; SMN2 | |
| SCHEMBL17967333 | 0.77 | SLC16A3 (0.48) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL7568147 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL4496916 | 0.76 | AKR1C3 (0.58) | KDM4EALDH1A1HPGDPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030195224-A1 | Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4- amines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195224-A1 | Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4- amines and analogs thereof | IFNG, THPO, IL2 | KDM4E 1959/4885ALDH1A1 2933/4885HPGD 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.