Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791036 | 0.63 | CACNA1B (0.46) | CACNA1BAPBA1MAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL12635405 | 0.62 | GRM2 (0.51) | MAOA | |
| SCHEMBL3534265 | 0.61 | MAOA (0.36) | CACNA1BAPBA1MAOASMN1; SMN2ALDH1A1 | |
| SCHEMBL26733431 | 0.58 | AKR1B1 (0.40) | SMN1; SMN2HTTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL10698564 | 0.58 | MAOA (0.42) | MAOASMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL1461676 | 0.57 | AR (0.47) | CACNA1BAPBA1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11469490 | 0.57 | CACNA1B (0.47) | CACNA1BAPBA1MAOAALDH1A1CYP1A2 | |
| SCHEMBL6224475 | 0.57 | MMP13 (0.40) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL22054799 | 0.57 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9731036 | 0.56 | MAOA (0.43) | CACNA1BAPBA1MAOASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026848-A1 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS | LUPIN LIMITED (IN) | 2004-04-01 | — | — | WO | disclosed |