Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27506261 | 1.00 | KMT2A (0.50) | KMT2AMEN1MAPTALDH1A1CYP2D6 | |
| SCHEMBL6321668 | 0.86 | KMT2A (0.44) | KMT2AMEN1MAPTALDH1A1CYP2D6 | |
| SCHEMBL6317128 | 0.84 | TACR1 (0.45) | KMT2AMEN1MAPTALDH1A1CYP2D6 | |
| SCHEMBL6318879 | 0.72 | OPRK1 (0.56) | ALDH1A1LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL27487738 | 0.72 | OPRK1 (0.56) | ALDH1A1LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL27488811 | 0.70 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL7065014 | 0.70 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL6318927 | 0.70 | HPGD (0.50) | MAPTALDH1A1RAB9ANPC1OPRM1 | |
| SCHEMBL19385457 | 0.70 | HPGD (0.50) | MAPTALDH1A1RAB9ANPC1OPRM1 | |
| SCHEMBL7064800 | 0.69 | HPGD (0.49) | RAB9ANPC1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055261-A1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS (U.S.), INC. | 2003-03-20 | — | — | US | disclosed |
| CN-1211991-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1999-03-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055261-A1 | Compounds with growth hormone releasing properties | GHRHR, GHSR, IGFBP1 | KMT2A 3089/4885MEN1 155/4885MAPT 4183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.