Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | NMT2 | O60551 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063575 | 0.90 | JAK2 (0.40) | KDM4ELMNAHTTNMT2NMT1 | |
| SCHEMBL5862104 | 0.83 | PLAUR (0.44) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL5859916 | 0.78 | RAB9A (0.49) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL5859258 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL6096967 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL5859907 | 0.76 | RAB9A (0.49) | ALDH1A1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL6097512 | 0.75 | HSD17B10 (0.51) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL5859257 | 0.75 | HTT (0.45) | ALDH1A1HPGDHSD17B10KDM4EHTT | |
| SCHEMBL6096131 | 0.75 | HSD17B10 (0.48) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL5859929 | 0.73 | TDP1 (0.41) | HTTSCN9ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314712-A1 | NF-KAPPA-B INHIBITOR CONTAINING SUBSTITUTED BENZOIC ACID DERIVATIVE AS ACTIVE INGREDIENT | Daiichi Suntory Pharma Co., Ltd. (JP) | 2003-05-28 | — | — | EP | disclosed |