Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835741 | 0.93 | NFKB1 (0.57) | AKR1C2AKR1C1NFKB1MAPTALDH1A1 | |
| SCHEMBL6834682 | 0.83 | SORT1 (0.60) | AKR1C2AKR1C1NFKB1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL31278027 | 0.80 | KDM4E (0.58) | NFKB1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL14075210 | 0.78 | PLK1 (0.69) | AKR1C2AKR1C1POLBPLK1PLK3 | |
| SCHEMBL31277577 | 0.76 | ALDH1A1 (0.58) | NFKB1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL28610631 | 0.75 | NPC1 (0.60) | NFKB1MAPTPOLBMEN1KMT2A | |
| SCHEMBL29643934 | 0.75 | NPC1 (0.60) | NFKB1MAPTPOLBMEN1KMT2A | |
| SCHEMBL6833242 | 0.74 | PLK1 (0.58) | AKR1C2AKR1C1POLBKDM4EMEN1 | |
| SCHEMBL6833147 | 0.73 | POLB (0.53) | AKR1C2AKR1C1MAPTPOLBKDM4E | |
| SCHEMBL6833223 | 0.73 | POLB (0.52) | AKR1C2AKR1C1POLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |