Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065806 | 0.85 | NAMPT (0.36) | MEN1CYP3A4KMT2AHRH2HRH1 | |
| SCHEMBL7064158 | 0.84 | KDM4E (0.36) | MEN1KMT2A | |
| SCHEMBL7063010 | 0.74 | RBP4 (0.38) | MEN1KMT2A | |
| SCHEMBL7065196 | 0.71 | NPC1 (0.32) | — | |
| SCHEMBL7612097 | 0.66 | KDM4E (0.38) | — | |
| SCHEMBL7612083 | 0.64 | KDM4E (0.36) | — | |
| SCHEMBL5830005 | 0.64 | ITGAL (0.42) | MEN1KMT2A | |
| SCHEMBL7065799 | 0.63 | GPR183 (0.36) | MEN1KMT2A | |
| SCHEMBL6817245 | 0.62 | ALDH1A1 (0.39) | CYP3A4 | |
| SCHEMBL6918676 | 0.62 | ALDH1A1 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |