Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 4/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298229 | 0.95 | POLB (0.42) | ABHD6DAGLAPOLBL3MBTL1LTA4H | |
| SCHEMBL7059997 | 0.95 | POLB (0.42) | ABHD6DAGLAPOLBL3MBTL1LTA4H | |
| SCHEMBL2560957 | 0.81 | PDE8B (0.43) | HPGD | |
| SCHEMBL2567398 | 0.81 | HSD17B10 (0.34) | ABHD6DAGLAPOLBNPC1RAB9A | |
| SCHEMBL31218628 | 0.81 | PDE8B (0.43) | HPGD | |
| SCHEMBL13695531 | 0.80 | CHRNB2 (0.48) | — | |
| SCHEMBL3828293 | 0.80 | POLB (0.38) | POLBL3MBTL1FFAR1RAB9A | |
| SCHEMBL15798117 | 0.79 | POLB (0.39) | ABHD6DAGLAPOLBL3MBTL1LTA4H | |
| SCHEMBL15798207 | 0.79 | POLB (0.39) | ABHD6DAGLAPOLBL3MBTL1LTA4H | |
| SCHEMBL1421475 | 0.79 | POLB (0.45) | POLBL3MBTL1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055261-A1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS (U.S.), INC. | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055261-A1 | Compounds with growth hormone releasing properties | GHRHR, GHSR, IGFBP1 | ABHD6 339/4885DAGLA 501/4885POLB 3553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.