SCHEMBL7066112

SCHEMBL7066112

Nc1c2ccoc2cc2oc(=O)c(C(=O)O)cc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 7/20 0.47
ALDH1A1 P00352 5/20 0.46
HPGD P15428 4/20 0.46
KDM4E B2RXH2 3/20 0.46
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
CA12 O43570 4/20 0.44
CA1 P00915 4/20 0.44
CA6 P23280 4/20 0.44
CA7 P43166 4/20 0.44
CA9 Q16790 4/20 0.44
CA14 Q9ULX7 4/20 0.44
CA5B Q9Y2D0 4/20 0.44
CA4 P22748 3/20 0.44
CA5A P35218 3/20 0.44
MAOB P27338 3/20 0.44
CA3 P07451 3/20 0.44
TSHR P16473 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7064690 0.84 ALDH1A1 (0.59) GPR35ALDH1A1HPGDKDM4EGLA
SCHEMBL4415644 0.74 CYP3A4 (0.42) ALDH1A1HPGDKDM4EMAOBTSHR
SCHEMBL2385579 0.72 GPR35 (0.59) GPR35ALDH1A1HPGDKDM4ECA12
SCHEMBL28007893 0.72 CYP1A1 (0.40) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL25142173 0.67 MAOB (0.61) GPR35ALDH1A1HPGDKDM4EGLA
SCHEMBL31113776 0.67 GPR35 (0.50) GPR35ALDH1A1HPGDKDM4EGLA
SCHEMBL7062287 0.66 GPR35 (0.56) GPR35ALDH1A1HPGDCA12CA1
SCHEMBL10516994 0.65 FTO (0.53) ALDH1A1KDM4ECA12CA1CA7
SCHEMBL30738443 0.65 MAOA (0.69) GPR35ALDH1A1HPGDKDM4EGLA
SCHEMBL28572247 0.65 GPR35 (0.60) GPR35ALDH1A1HPGDKDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030219755-A1 Compositions and methods for performing hybridization assays using target enhanced signal amplification (TESA) APPLIED GENE TECHNOLOGIES, INC. 2003-11-27 US claimed
US-20030219755-A1 Compositions and methods for performing hybridization assays using target enhanced signal amplification (TESA) APPLIED GENE TECHNOLOGIES, INC. 2003-11-27 US disclosed
US-5026840-A For hybridization assays MOLECULAR DIAGNOSTICS, INC. (US) 1991-06-25 US disclosed
US-4950744-A FOR HYBRIDIZATION ASSAYS; PROBES MOLECULAR DIAGNOSTICS, INC. (US) 1990-08-21 US disclosed