Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655880 | 0.71 | MMP9 (0.55) | L3MBTL1MMP9ALDH1A1KDM4ETSHR | |
| SCHEMBL7443157 | 0.70 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KDM4EGSK3BKMT2A | |
| SCHEMBL7470147 | 0.70 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KDM4EGSK3BKMT2A | |
| SCHEMBL29076347 | 0.70 | MMP9 (0.46) | MMP9ALDH1A1KDM4ETSHRSIGMAR1 | |
| SCHEMBL11220240 | 0.70 | RAB9A (0.60) | L3MBTL1MMP9ALDH1A1KDM4ETSHR | |
| SCHEMBL14229516 | 0.70 | TP53 (0.50) | L3MBTL1MMP9ALDH1A1KDM4ETSHR | |
| SCHEMBL3807502 | 0.70 | SIGMAR1 (0.62) | L3MBTL1MMP9ALDH1A1KDM4ETSHR | |
| SCHEMBL13007694 | 0.70 | SIGMAR1 (0.61) | L3MBTL1ALDH1A1KDM4ETSHRSIGMAR1 | |
| SCHEMBL1833549 | 0.68 | MEN1 (0.52) | ALDH1A1KDM4ESIGMAR1KMT2ARAB9A | |
| SCHEMBL11516064 | 0.68 | SIGMAR1 (0.49) | L3MBTL1MMP9ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178953-B1 | AROMATIC AMIDES | WARNER LAMBERT CO (US) | 2003-12-03 | — | — | EP | claimed |