Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486400 | 0.76 | POLB (0.40) | HPGDL3MBTL1 | |
| SCHEMBL29191703 | 0.71 | NOTUM (0.41) | HPGDRAB9AL3MBTL1 | |
| SCHEMBL9060888 | 0.71 | ALDH1A1 (0.40) | HPGDL3MBTL1 | |
| SCHEMBL9178589 | 0.68 | MAPT (0.51) | RAB9AL3MBTL1 | |
| SCHEMBL27567042 | 0.66 | GAA (0.59) | HPGDRAB9A | |
| SCHEMBL6667756 | 0.64 | ALDH1A1 (0.46) | HPGDRAB9AL3MBTL1 | |
| SCHEMBL3014252 | 0.64 | ALDH1A1 (0.36) | HPGDRAB9AL3MBTL1 | |
| SCHEMBL7256137 | 0.62 | ALDH1A1 (0.38) | HPGDRAB9AL3MBTL1 | |
| SCHEMBL1394908 | 0.61 | KMT2A (0.39) | HPGDRAB9AL3MBTL1 | |
| SCHEMBL7938811 | 0.61 | ALDH1A1 (0.37) | HPGDRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140851-B1 | 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | UPJOHN CO (US) | 2004-09-01 | — | — | EP | disclosed |
| EP-1140851-A1 | 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6248736-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |
| WO-2000040563-A1 | 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |