Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175519 | 0.83 | SHMT2 (0.34) | ALDH1A1MAPTKDM4ETSHRMEN1 | |
| SCHEMBL4764684 | 0.82 | SHMT2 (0.39) | ALDH1A1MAPTKDM4ETSHRMEN1 | |
| SCHEMBL14311341 | 0.82 | ALDH1A1 (0.34) | ALDH1A1MAPTKDM4ETSHRMEN1 | |
| SCHEMBL19211201 | 0.82 | ALDH1A1 (0.34) | ALDH1A1MAPTKDM4ETSHRMEN1 | |
| SCHEMBL8780480 | 0.80 | PTPN1 (0.35) | ALDH1A1MAPTKDM4ETSHRAPAF1 | |
| SCHEMBL2821603 | 0.79 | PTPN1 (0.40) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 | |
| SCHEMBL9176975 | 0.78 | KDM4E (0.32) | ALDH1A1MAPTKDM4ETSHRMEN1 | |
| SCHEMBL472874 | 0.78 | LMNA (0.34) | ALDH1A1MAPTKDM4ETSHRMEN1 | |
| SCHEMBL21065455 | 0.78 | PTPN1 (0.42) | TSHRL3MBTL1LMNACES1TDP1 | |
| Phosphoric Acid SCHEMBL27784283 | 0.77 | CETP (0.39) | MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100196476-A1 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | FUNDACAO UNIVERSIDADE FEDERAL DE SAO CARLOS (BR) | 2010-08-05 | — | — | US | claimed |
| EP-2167468-A2 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | Fundação Universidade Federal De São Carlos (BR) | 2010-03-31 | — | — | EP | claimed |
| WO-2008144865-A2 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | FUNDAÇÃO UNIVERSIDADE FEDERAL DE SÃO CARLOS (BR) | 2008-12-04 | — | — | WO | claimed |
| US-20100196476-A1 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | FUNDACAO UNIVERSIDADE FEDERAL DE SAO CARLOS (BR) | 2010-08-05 | — | — | US | disclosed |
| EP-2167468-A2 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | Fundação Universidade Federal De São Carlos (BR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008144865-A2 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | FUNDAÇÃO UNIVERSIDADE FEDERAL DE SÃO CARLOS (BR) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100196476-A1 | PROCESS FOR THE PREPARATION AND PHARMACEUTICAL FORMULATIONS FOR 4-QUINOLINONES AND QUINOLINES AND USE THEREOF | PF4, KCNQ1, KCNQ2 | ALDH1A1 2185/4885MAPT 3852/4885KDM4E 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.