Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | APAF1 | O14727 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GALK1 | P51570 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | GSK3A | P49840 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339071 | 0.80 | POLB (0.38) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6667756 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDBCHECES1 | |
| SCHEMBL28496097 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDBCHECES1 | |
| SCHEMBL7938811 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDBCHECES1 | |
| SCHEMBL1394908 | 0.78 | KMT2A (0.39) | ALDH1A1KDM4EHPGDBCHECES1 | |
| SCHEMBL9179316 | 0.77 | MAPT (0.39) | ALDH1A1KDM4EHPGDBCHECES1 | |
| SCHEMBL8829422 | 0.75 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDBCHECES1 | |
| SCHEMBL28853158 | 0.75 | ACHE (0.31) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL367269 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4764684 | 0.73 | SHMT2 (0.39) | ALDH1A1KDM4EHPGDBCHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440407-A | A kind of preparation method for the chloro- 6- nitros -7- fluorine quinoline of 4- that Vilsmeier reagents participate in | 郭丽 | 2018-08-24 | — | — | CN | claimed |
| CN-104803913-B | A kind of carbonic acid benzylquinolin base ester type compound, preparation method and application | 浙江省化工研究院有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-108440407-A | A kind of preparation method for the chloro- 6- nitros -7- fluorine quinoline of 4- that Vilsmeier reagents participate in | 郭丽 | 2018-08-24 | — | — | CN | disclosed |
| CN-107438598-A | QUINAZOLINE AND QUINOLINE COMPOUNDS AND USES THEREOF | 米伦纽姆医药公司 | 2017-12-05 | — | — | CN | disclosed |
| CN-106660994-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-106573922-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-106458932-A | Phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-103435601-B | One class Mutiple Targets flavones-quinolinone type compound and method for making thereof and purposes | JISHOU UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-103483321-A | Alkyl linked pyridoin-quinolinone compounds and preparation method as well as application thereof | UNIV JISHOU | 2014-01-01 | — | — | CN | disclosed |
| CN-103435601-A | Multiple-target-point flavone-quinolinone compound and preparation method and applications thereof | UNIV JISHOU | 2013-12-11 | — | — | CN | disclosed |
| CN-103435600-A | Alkyl connection quinolinone-furanone compounds and preparation method and application thereof | UNIV JISHOU | 2013-12-11 | — | — | CN | disclosed |
| CN-103435611-A | Multi-target point alpha-pyridoin compounds and preparation method and application thereof | UNIV JISHOU | 2013-12-11 | — | — | CN | disclosed |
| CN-103421008-A | Multiple target point furanone-quinolinone compounds and preparation method and usage of multiple target point furanone-quinolinone compounds | UNIV JISHOU | 2013-12-04 | — | — | CN | disclosed |
| CN-103153063-A | Quinoline derivatives and MELK inhibitors containing the same | ONCOTHERAPY SCIENCE INC | 2013-06-12 | — | — | CN | disclosed |
| CN-103153096-A | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | SENOMYX INC | 2013-06-12 | — | — | CN | disclosed |
| US-6528517-B1 | Solid phase synthesis | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2003-03-04 | — | — | US | disclosed |
| WO-1999040093-A2 | SYNTHESIS OF QUINOBENZOXAZINE ANALOGUES WITH TOPOISOMERASE II AND QUADRUPLEX INTERACTIONS FOR USE AS ANTINEOPLASTIC AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-08-12 | — | — | WO | disclosed |