Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066635 | 0.84 | MAPT (0.48) | MEN1ALDH1A1HTTKMT2AGFER | |
| SCHEMBL7254034 | 0.81 | GFER (0.65) | MEN1ALDH1A1HTTKMT2AGFER | |
| SCHEMBL7253167 | 0.75 | MEN1 (0.51) | MEN1ALDH1A1HTTKMT2AITGB3 | |
| SCHEMBL6695190 | 0.75 | ALDH1A1 (0.50) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL7066698 | 0.75 | DRD4 (0.52) | MEN1ALDH1A1HTTKMT2AITGB3 | |
| SCHEMBL21258355 | 0.73 | ALOX5 (0.42) | MEN1ALDH1A1KMT2A | |
| SCHEMBL6694937 | 0.73 | ITGB3 (0.56) | ITGB3ITGA2BHTR2AHTR2CHTR2B | |
| SCHEMBL7068726 | 0.72 | DRD2 (0.69) | MEN1ALDH1A1HTTKMT2AADORA1 | |
| Hydrochloric Acid SCHEMBL6700195 | 0.72 | ITGB3 (0.55) | ITGB3ITGA2BHTR2AHTR2CHTR2B | |
| SCHEMBL2744427 | 0.71 | HTR2A (0.69) | ITGB3ITGA2BHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |