SCHEMBL23376907

SCHEMBL23376907

CNC(=O)C(Cc1ccccc1)NC(=O)CCC=O

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MMP1 P03956 16/20 0.56
▸ FCER2 P06734 2/20 0.56
▸ MMP3 P08254 13/20 0.52
▸ MMP2 P08253 10/20 0.52
▸ MMP8 P22894 7/20 0.52
▸ MMP7 P09237 7/20 0.52
▸ MMP9 P14780 4/20 0.52
▸ CTSL P07711 1/20 0.49
▸ CTSB P07858 1/20 0.49
▸ CTSS P25774 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066963 0.87 MMP1 (0.61) MMP1FCER2MMP3MMP2MMP8
SCHEMBL7066966 0.87 MMP1 (0.61) MMP1FCER2MMP3MMP2MMP8
SCHEMBL10441159 0.86 ACE (0.59) —
SCHEMBL989841 0.85 PSMB5 (0.64) MMP1FCER2MMP3MMP2MMP8
SCHEMBL15759462 0.85 PSMB5 (0.64) MMP1FCER2MMP3MMP2MMP8
SCHEMBL7391831 0.82 MMP1 (0.57) MMP1FCER2MMP3MMP2MMP8
SCHEMBL7277442 0.82 MMP1 (0.59) MMP1FCER2MMP3MMP2MMP8
SCHEMBL25000564 0.81 MMP1 (0.63) MMP1FCER2MMP3MMP2MMP8
SCHEMBL25139508 0.81 MMP1 (0.63) MMP1FCER2MMP3MMP2MMP8
SCHEMBL13956893 0.81 MMP1 (0.60) MMP1FCER2MMP3MMP2MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11560401-B2 Method for preparing oligonucleic acid compound NIPPON SHINYAKU CO., LTD. (JP) 2023-01-24 — — US disclosed
US-20230014840-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2023-01-19 — — US disclosed
US-20230018780-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2023-01-19 — — US disclosed
WO-2021095874-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND 日本新薬株式会社 2021-05-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230018780-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND POLRMT, POLR2H, POLM MMP1 1529/4885FCER2 4881/4885MMP3 2430/4885
US-11560401-B2 Method for preparing oligonucleic acid compound POLRMT, POLI, POLR2H MMP1 2872/4885FCER2 4882/4885MMP3 3939/4885
US-20230014840-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND DNASE1, XRN2, FBL MMP1 2406/4885FCER2 4675/4885MMP3 3548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback