Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18013115 | 0.92 | KEAP1 (0.46) | KEAP1NFE2L2AKR1C2AKR1C1CA1 | |
| SCHEMBL14331830 | 0.85 | KEAP1 (0.50) | KEAP1NFE2L2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL7842740 | 0.84 | HPGD (0.38) | KEAP1NFE2L2AKR1C2AKR1C1CA1 | |
| SCHEMBL23706639 | 0.83 | PYGL (0.50) | KEAP1NFE2L2AKR1C2AKR1C1CA1 | |
| SCHEMBL223134 | 0.83 | KEAP1 (0.53) | KEAP1NFE2L2AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL22222257 | 0.82 | KDM4E (0.47) | KEAP1NFE2L2AKR1C2AKR1C1CA1 | |
| SCHEMBL30892458 | 0.82 | KDM4E (0.47) | KEAP1NFE2L2AKR1C2AKR1C1CA1 | |
| SCHEMBL9618645 | 0.82 | HSP90AA1 (0.40) | KDM4ETSHRHPGDHSD17B10ALDH1A1 | |
| SCHEMBL25297555 | 0.80 | KDM4E (0.45) | KEAP1NFE2L2AKR1C2AKR1C1CA1 | |
| SCHEMBL8279091 | 0.80 | CA1 (0.57) | AKR1C2AKR1C1CA1CA2AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055843-A1 | AGARICOGLYCERIDES AND ANALOGS | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | disclosed |