Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA7 | P43166 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070294 | 0.84 | GAA (0.56) | F10SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7074652 | 0.83 | F2 (0.54) | SMN1; SMN2MEN1KMT2ATSHRALDH1A1 | |
| Acetic Acid SCHEMBL27568113 | 0.81 | GAA (0.56) | F10SMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL7126859 | 0.80 | ALDH1A1 (0.62) | F10SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7076666 | 0.77 | LMNA (0.72) | F10MEN1KMT2ALMNAALDH1A1 | |
| Acetic Acid SCHEMBL27525154 | 0.77 | ALDH1A1 (0.59) | F10SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7074220 | 0.77 | LMNA (0.71) | F10MEN1KMT2ALMNAALDH1A1 | |
| Acetic Acid SCHEMBL28744327 | 0.76 | LMNA (0.70) | F10SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL7074494 | 0.76 | F10 (0.66) | F10MEN1KMT2ALMNACA12 | |
| SCHEMBL7071435 | 0.76 | KMT2A (0.64) | F10MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |