SCHEMBL7070701

SCHEMBL7070701

Fc1nc2cccc(Cl)c2c(Oc2ccccc2)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.44
MAPT P10636 1/20 0.44
ELANE P08246 4/20 0.41
DPP4 P27487 1/20 0.36
KDM1A O60341 1/20 0.36
ALDH1A1 P00352 2/20 0.34
HTT P42858 1/20 0.34
PARP1 P09874 1/20 0.34
RHEB Q15382 1/20 0.33
DHODH Q02127 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PGR P06401 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9645022 0.69 LTA4H (0.52) KMT2AKDM4EGLAMAPTDPP4
SCHEMBL538143 0.69 PARP1 (0.42) ELANEPARP1
Diphenylether SCHEMBL7948020 0.65 LTA4H (0.60) MAPTDPP4ALDH1A1MAOAMAOB
SCHEMBL10654059 0.65 MAOA (0.65) KMT2AKDM4EGLAMAPTELANE
SCHEMBL6921888 0.64 KMT2A (0.50) KMT2AKDM4EGLAMAPTKDM1A
SCHEMBL3784924 0.63 DPP4 (0.59) KMT2AMAPTDPP4KDM1AALDH1A1
SCHEMBL3689752 0.63 LTA4H (0.55) KMT2AKDM4EGLAMAPTDPP4
SCHEMBL11660811 0.63 STK39 (0.46) KMT2AKDM4EGLAMAPTALDH1A1
SCHEMBL6691486 0.63 ALDH1A1 (0.48) KMT2AMAPTALDH1A1MEN1NPSR1
Diphenylether SCHEMBL18588103 0.62 LTA4H (0.71) DPP4MAOAMAOBPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1315702-A2 PROCESS TO PRODUCE HALO-4-PHENOXYQUINOLINES Dow AgroSciences LLC (US) 2003-06-04 EP disclosed
WO-2002020490-A2 PROCESS TO PRODUCE HALO-4-PHENOXYQUINOLINES DOW AGROSCIENCES LLC (US) 2002-03-14 WO disclosed