Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | CASP4 | P49662 | 2/20 | 0.37 |
| ▸ | CASP5 | P51878 | 2/20 | 0.37 |
| ▸ | CASP9 | P55211 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.37 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | GRPR | P30550 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253193 | 0.94 | PTPN1 (0.43) | TASP1PTPN1F2CASP3CASP7 | |
| SCHEMBL31094977 | 0.83 | PTPN1 (0.46) | PTPN1F2BACE1BACE2KEAP1 | |
| SCHEMBL6687472 | 0.82 | CASP1 (0.46) | PTPN1F2CASP1CASP3CASP9 | |
| SCHEMBL29310044 | 0.80 | PTPN1 (0.43) | PTPN1F2BACE1BACE2KEAP1 | |
| SCHEMBL31187019 | 0.79 | BACE1 (0.42) | F2CASP1CASP3CASP4CASP5 | |
| SCHEMBL21529464 | 0.79 | BACE1 (0.42) | F2CASP1CASP3CASP4CASP5 | |
| SCHEMBL21481062 | 0.78 | CTSL (0.49) | CASP1CASP3CASP4CASP5CASP9 | |
| SCHEMBL18328829 | 0.78 | CTSL (0.49) | CASP1CASP3CASP4CASP5CASP9 | |
| SCHEMBL1548820 | 0.78 | CTSL (0.49) | CASP1CASP3CASP4CASP5CASP9 | |
| SCHEMBL29310045 | 0.78 | PTPN1 (0.42) | PTPN1F2GRPRBACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055103-A1 | Utilization of achyrocline satureoides (\"Marcela\") extracts and liposomal preparations of natural and semi-synthetic flavonoids for the prevention and treatment of the consequences of stroke and neurodegenerative diseases | HEINZEN HORACIO (UY) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055103-A1 | Utilization of achyrocline satureoides (\"Marcela\") extracts and liposomal preparations of natural and semi-synthetic flavonoids for the prevention and treatment of the consequences of stroke and neurodegenerative diseases | ACHE, KYNU, NLN | TASP1 859/4885PTPN1 3625/4885F2 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.