Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 5/20 | 0.46 |
| ▸ | CASP3 | P42574 | 4/20 | 0.46 |
| ▸ | CASP9 | P55211 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | CPA2 | P48052 | 1/20 | 0.37 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253193 | 0.87 | PTPN1 (0.43) | CASP3BACE1BACE2F2PTPN1 | |
| SCHEMBL1548820 | 0.83 | CTSL (0.49) | CASP1CASP3CASP9CASP7MMP1 | |
| SCHEMBL18328829 | 0.83 | CTSL (0.49) | CASP1CASP3CASP9CASP7MMP1 | |
| SCHEMBL21481062 | 0.83 | CTSL (0.49) | CASP1CASP3CASP9CASP7MMP1 | |
| SCHEMBL7444999 | 0.82 | OPRD1 (0.49) | CASP1CASP3CASP9CASP7 | |
| SCHEMBL7070816 | 0.82 | TASP1 (0.48) | CASP1CASP3CASP9BACE1BACE2 | |
| SCHEMBL30753845 | 0.80 | NAALAD2 (0.51) | CASP1CASP3CASP9BACE1BACE2 | |
| SCHEMBL9961759 | 0.79 | CASP3 (0.66) | CASP1CASP3CASP9CASP7 | |
| SCHEMBL30688994 | 0.79 | NAALAD2 (0.52) | BACE1BACE2NAALAD2ENPEP | |
| SCHEMBL19051569 | 0.79 | GNPAT (0.40) | BACE1BACE2PTPN1NAALAD2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056386-A2 | NUCLEIC ACIDS INVOLVED IN BLOOD-BRAIN BARRIER CONTROL | TO-BBB HOLDING B.V. (NL) | 2004-07-08 | — | — | WO | disclosed |