Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | CASP1 | P29466 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071541 | 0.74 | KDM4E (0.44) | KDM4EL3MBTL1MAPTTDP1HPGDS | |
| SCHEMBL18762307 | 0.69 | MTNR1A (0.42) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18762308 | 0.69 | MTNR1A (0.42) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18805363 | 0.68 | ALDH1A1 (0.48) | NQO1KDM4EALDH1A1HPGDNCOA1 | |
| SCHEMBL17586641 | 0.65 | CDK1 (0.56) | KDM4EALDH1A1GAACLK1HSD17B10 | |
| SCHEMBL17582786 | 0.65 | NCF1 (0.46) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL28326492 | 0.64 | KDM4E (0.45) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL4602088 | 0.63 | KDM4E (0.61) | NQO1KDM4EL3MBTL1CASP1ALDH1A1 | |
| SCHEMBL21985970 | 0.63 | PDE2A (0.44) | KDM4EALDH1A1HPGDNCOA1NCOA3 | |
| SCHEMBL906879 | 0.62 | NQO1 (1.00) | NQO1KDM4EL3MBTL1CASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216582-A1 | 2-CARBOXAMIDE-BENZIMIDAZOLES USEFUL IN THE TREATMENT AND PREVENTION OF ISCHEMIC REPERFUSION INJURY | NIKOLAIDES NICHOLAS (US) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216582-A1 | 2-CARBOXAMIDE-BENZIMIDAZOLES USEFUL IN THE TREATMENT AND PREVENTION OF ISCHEMIC REPERFUSION INJURY | CBR3, BAK1, CBR1 | NQO1 827/4885KDM4E 2913/4885L3MBTL1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.