Acrylic Acid

Acrylic Acid

SCHEMBL7071287

C=CC(=O)O.C=CCNCC=C

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TSHR P16473 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 4/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HPGD P15428 1/20 0.34
FAAH O00519 1/20 0.33
HTT P42858 1/20 0.33
TGM2 P21980 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL2790689 0.97 LMNA (0.53) LMNAALOX15HSD17B10TSHRSMN1; SMN2
Acrylic Acid SCHEMBL27988712 0.95 LMNA (0.50) LMNAALOX15HSD17B10TSHRSMN1; SMN2
Acrylic Acid SCHEMBL1232457 0.91 ALDH1A1 (0.50) LMNAALOX15HSD17B10TSHRSMN1; SMN2
Acrylic Acid SCHEMBL546829 0.89 ALDH1A1 (0.48) LMNAALOX15HSD17B10TSHRSMN1; SMN2
Maleic Acid SCHEMBL16228194 0.86 TSHR (0.47) LMNAALOX15HSD17B10TSHRSMN1; SMN2
Fumaric Acid SCHEMBL16228196 0.86 TSHR (0.47) LMNAALOX15HSD17B10TSHRSMN1; SMN2
Maleic Acid SCHEMBL1639455 0.84 TSHR (0.45) LMNAALOX15HSD17B10TSHRSMN1; SMN2
Fumaric Acid SCHEMBL1639460 0.84 TSHR (0.45) LMNAALOX15HSD17B10TSHRSMN1; SMN2
Acetic Acid SCHEMBL28451525 0.83 SMN1; SMN2 (0.41) LMNATSHRSMN1; SMN2MAPTKMT2A
Acetic Acid SCHEMBL968509 0.83 SMN1; SMN2 (0.41) LMNATSHRSMN1; SMN2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040019146-A1 Elastomeric polyurethane fiber with high heat-set efficiency INVISTA NORTH AMERICA S.A.R.L. (F/K/A ARTEVA NORTH AMERICA S.A.R.L.) 2004-01-29 US claimed
EP-1356144-A1 ELASTOMERIC POLYURETHANE FIBER WITH HIGH HEAT-SET EFFICIENCY DuPont-Toray Co. Ltd. (JP) 2003-10-29 EP claimed
WO-2002050349-A1 ELASTOMERIC POLYURETHANE FIBER WITH HIGH HEAT-SET EFFICIENCY DUPONT-TORAY COMPANY, LTD (JP) 2002-06-27 WO claimed
US-9452426-B2 Polymer adsorbent NIPPON FILCON CO., LIMITED (JP) 2016-09-27 US disclosed
EP-2808080-A1 POLYMER ADSORBENT Nippon Filcon Co., Ltd. (JP) 2014-12-03 EP disclosed
US-20140332714-A1 POLYMER ADSORBENT NIPPON FILCON CO., LIMITED (JP) 2014-11-13 US disclosed
US-20040019146-A1 Elastomeric polyurethane fiber with high heat-set efficiency INVISTA NORTH AMERICA S.A.R.L. (F/K/A ARTEVA NORTH AMERICA S.A.R.L.) 2004-01-29 US disclosed
EP-1356144-A1 ELASTOMERIC POLYURETHANE FIBER WITH HIGH HEAT-SET EFFICIENCY DuPont-Toray Co. Ltd. (JP) 2003-10-29 EP disclosed
WO-2002050349-A1 ELASTOMERIC POLYURETHANE FIBER WITH HIGH HEAT-SET EFFICIENCY DUPONT-TORAY COMPANY, LTD (JP) 2002-06-27 WO disclosed
US-5865951-A USING A NEUTRAL SIZING AGENT AND CATIONIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed