Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL1232457 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TSHRFGFR4LMNAALOX15 | |
| Acrylamide SCHEMBL546914 | 0.93 | TSHR (0.55) | ALDH1A1TSHRFGFR4LMNASMN1; SMN2 | |
| Acrylamide SCHEMBL12080466 | 0.93 | TSHR (0.55) | ALDH1A1TSHRFGFR4LMNASMN1; SMN2 | |
| Acrylic Acid SCHEMBL2790689 | 0.91 | LMNA (0.53) | ALDH1A1TSHRLMNAALOX15HSD17B10 | |
| Acrylamide SCHEMBL546706 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRFGFR4LMNASMN1; SMN2 | |
| Acrylic Acid SCHEMBL27988712 | 0.89 | LMNA (0.50) | ALDH1A1TSHRLMNAALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL7071287 | 0.89 | LMNA (0.56) | ALDH1A1TSHRLMNAALOX15HSD17B10 | |
| Urea SCHEMBL27483216 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRFGFR4LMNASMN1; SMN2 | |
| Acrylic Acid SCHEMBL15738493 | 0.81 | ALDH1A1 (0.73) | ALDH1A1TSHRFGFR4LMNAALOX15 | |
| Maleic Acid SCHEMBL1639455 | 0.79 | TSHR (0.45) | ALDH1A1TSHRLMNAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161920-B2 | Method for producing carboxyl-group-containing nitrile rubber | ZEON CORPORATION (JP) | 2021-11-02 | — | — | US | disclosed |
| EP-3604397-B1 | METHOD FOR PRODUCING CARBOXYL-GROUP-CONTAINING NITRILE RUBBER | ZEON CORP (JP) | 2021-10-13 | — | — | EP | disclosed |
| EP-3604397-A1 | METHOD FOR PRODUCING CARBOXYL-GROUP-CONTAINING NITRILE RUBBER | Zeon Corporation (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-20200031955-A1 | METHOD FOR PRODUCING CARBOXYL-GROUP-CONTAINING NITRILE RUBBER | ZEON CORPORATION (JP) | 2020-01-30 | — | — | US | disclosed |
| US-10457079-B2 | Ink, inkjet recording method, ink cartridge, and image recording device | RICOH COMPANY, LTD. (JP) | 2019-10-29 | — | — | US | disclosed |
| EP-2705834-B1 | CLEANING AGENT COMPOSITION | KAO CORP (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-20190111715-A1 | INK, INKJET RECORDING METHOD, INK CARTRIDGE, AND IMAGE RECORDING DEVICE | TOYAMA KAORI (JP) | 2019-04-18 | — | — | US | disclosed |
| EP-2052044-B1 | RECORDING INK, INK CARTRIDGE, INK MEDIA SET, INK- JET RECORDING METHOD AND INK-JET RECORDING APPARATUS | RICOH CO LTD (JP) | 2019-02-06 | — | — | EP | disclosed |
| US-10195885-B2 | Ink, inkjet recording method, ink cartridge, and image recording device | RICOH COMPANY, LTD. (JP) | 2019-02-05 | — | — | US | disclosed |
| US-20170361632-A1 | INK, INKJET RECORDING METHOD, INK CARTRIDGE, AND IMAGE RECORDING DEVICE | RICOH COMPANY, LTD. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20100196601-A1 | RECORDING INK, INK CARTRIDGE, INK MEDIA SET, INK- JET RECORDING METHOD AND INK-JET RECORDING APPARATUS | RICOH COMPANY, LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| EP-2178992-A1 | RECORDING INK, INK MEDIA SET, INK CARTRIDGE, INK RECORDED MATTER, INKJET RECORDING APPARATUS, AND INKJET RECORDING METHOD | Ricoh Company, Ltd. (JP) | 2010-04-28 | — | — | EP | disclosed |
| EP-2167593-A1 | INK-JET RECORDING INK, INK-JET RECORDING INK SET, INK-JET RECORDING INK MEDIA SET, INK CARTRIDGE, INK-JET RECORDING METHOD AND INK-JET RECORDING APPARATUS | Ricoh Company, Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009082000-A1 | INK-JET RECORDING INK, INK-JET RECORDING INK SET, INK-JET RECORDING INK MEDIA SET, INK CARTRIDGE, INK-JET RECORDING METHOD AND INK-JET RECORDING APPARATUS | RICOH COMPANY, LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009069721-A1 | INK-JET RECORDING INK, INK-JET RECORDING INK SET, INK-JET RECORDING INK MEDIA SET, INK CARTRIDGE, INK-JET RECORDING METHOD AND INK-JET RECORDING APPARATUS | RICOH COMPANY, LTD. (JP) | 2009-06-04 | — | — | WO | disclosed |
| EP-2064068-A1 | INK-JET RECORDING METHOD, INK-JET RECORDING APPARATUS AND RECORDED MATTER | Ricoh Company, Ltd. (JP) | 2009-06-03 | — | — | EP | disclosed |
| EP-2052044-A1 | RECORDING INK, INK CARTRIDGE, INK MEDIA SET, INK- JET RECORDING METHOD AND INK-JET RECORDING APPARATUS | Ricoh Company, Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
| WO-2009035158-A1 | RECORDING INK, INK MEDIA SET, INK CARTRIDGE, INK RECORDED MATTER, INKJET RECORDING APPARATUS, AND INKJET RECORDING METHOD | RICOH COMPANY, LTD. (JP) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009001967-A1 | INK-JET RECORDING METHOD, INK-JET RECORDING APPARATUS AND RECORDED MATTER | RICOH COMPANY, LTD. (JP) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008153203-A1 | RECORDING INK, INK CARTRIDGE, INK MEDIA SET, INK- JET RECORDING METHOD AND INK-JET RECORDING APPARATUS | RICOH COMPANY, LTD. (JP) | 2008-12-18 | — | — | WO | disclosed |