Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074249 | 0.87 | RAB9A (0.44) | TSHRRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7077103 | 0.84 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL5888403 | 0.77 | TSHR (0.46) | TSHRRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5888519 | 0.77 | MEN1 (0.60) | TSHRRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL7225023 | 0.77 | TSHR (0.49) | TSHRRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6230678 | 0.74 | TSHR (0.48) | TSHRRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6838100 | 0.74 | LTC4S (0.62) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6838097 | 0.74 | ALDH1A1 (0.48) | TSHRRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6902517 | 0.73 | TSHR (0.41) | TSHRRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6907335 | 0.72 | RAB9A (0.47) | TSHRRAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469034-B1 | TREATMENT OF HIV INFECTION, INCLUDING MUTANT, DRUG-SENSITIVE, DRUG- RESISTANT, AND MULTI-DRUG RESISTANT STRAINS | PARKER HUGHES INSTITUTE | 2002-10-22 | — | — | US | claimed |
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | PARKER HUGHES INSTITUTE | 2003-07-03 | — | — | US | disclosed |
| US-6469034-B1 | TREATMENT OF HIV INFECTION, INCLUDING MUTANT, DRUG-SENSITIVE, DRUG- RESISTANT, AND MULTI-DRUG RESISTANT STRAINS | PARKER HUGHES INSTITUTE | 2002-10-22 | — | — | US | disclosed |
| EP-1194149-A1 | CYCLOHEXENYL-ETHYL-THIOUREA COMPOUNDS AND USE | Parker Hughes Institute (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078315-A1 | CYCLOHEXENYL-ETHYL-THIOUREA COMPOUNDS AND USE | PARKER HUGHES INSTITUTE (US) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | TPMT, DNTT, BHMT | TSHR 1584/4885RAB9A 3078/4885NPC1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.