Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070559 | 0.81 | L3MBTL1 (0.47) | L3MBTL1TP53HDAC1HDAC6FFAR4 | |
| SCHEMBL7075442 | 0.80 | TSHR (0.45) | L3MBTL1TP53HDAC1HDAC6HDAC8 | |
| SCHEMBL7097280 | 0.79 | MAPT (0.45) | L3MBTL1TP53FFAR4DAORAB9A | |
| SCHEMBL12747582 | 0.75 | L3MBTL1 (0.62) | L3MBTL1TP53FFAR4DAOMET | |
| SCHEMBL7097848 | 0.74 | MAPT (0.41) | L3MBTL1TP53HDAC1HDAC6FFAR4 | |
| SCHEMBL7098774 | 0.74 | PDE4A (0.46) | TP53FFAR4RAB9ALMNANPC1 | |
| SCHEMBL15100794 | 0.73 | MGLL (0.65) | L3MBTL1TP53HDAC1HDAC6FFAR4 | |
| SCHEMBL7096610 | 0.73 | PDE4A (0.42) | L3MBTL1TP53HDAC1HDAC6FFAR4 | |
| SCHEMBL20408693 | 0.73 | MGLL (0.53) | L3MBTL1TP53HDAC1HDAC6FFAR4 | |
| SCHEMBL7116372 | 0.73 | L3MBTL1 (0.59) | L3MBTL1FFAR4DAOMETRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187037-A1 | Acetamide derivatives and the use thereof as inhibitors of coagulation factors xa and viia | MERCK-PATENT GMBH (DE) | 2003-10-02 | — | — | US | disclosed |
| US-20030171579-A1 | Urethane derivatives | MERCK PATENT GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187037-A1 | Acetamide derivatives and the use thereof as inhibitors of coagulation factors xa and viia | F12, F11, PLAT | L3MBTL1 2304/4885TP53 3831/4885HDAC1 297/4885 |
| US-20030171579-A1 | Urethane derivatives | UTS2R, PLAUR, IL1A | L3MBTL1 3573/4885TP53 4080/4885HDAC1 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.