Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.49 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.49 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20150563 | 0.90 | LMNA (0.45) | HTTKDM4EHSD17B10LMNAKMT2A | |
| SCHEMBL1467162 | 0.87 | GABRA1 (0.48) | HTTKDM4EHSD17B10LMNAKMT2A | |
| SCHEMBL5774340 | 0.87 | NHERF1 (0.47) | MAP2K4HTTCA12CA1CA9 | |
| SCHEMBL7074745 | 0.86 | CA12 (0.46) | MAPK1MAP2K4MAPKAPK3MAPK6HTT | |
| SCHEMBL7072427 | 0.86 | RAB9A (0.48) | HTTKDM4EHSD17B10LMNAKMT2A | |
| SCHEMBL5778119 | 0.84 | MAP2K4 (0.52) | MAPK1MAP2K4MAPKAPK3MAPK6HTT | |
| SCHEMBL5773359 | 0.84 | HTT (0.53) | MAPK1MAP2K4HTTCA12CA9 | |
| SCHEMBL5776599 | 0.83 | HTT (0.46) | MAPK1MAP2K4MAPKAPK3MAPK6HTT | |
| SCHEMBL20150514 | 0.83 | PDE4B (0.43) | KDM4EKMT2ARAB9AMEN1POLB | |
| SCHEMBL20150565 | 0.81 | NPBWR1 (0.43) | HTTKDM4EHSD17B10LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1249063-C | Novel Immunomodulatory Compounds | ACTIVE BIOTECH AB (SE) | 2006-04-05 | — | — | CN | disclosed |
| CN-1522254-A | Novel Immunomodulatory Compounds | ��Ծ���＼���ɷݹ�˾ | 2004-08-18 | — | — | CN | disclosed |
| US-6642249-B2 | 3-Oxo-pyrazolo(4,3-c) -quinolin-2-yl, -thiochroman-2-yl, or -chromen-2-yl derivatives; CD80 antagonists | ACTIVE BIOTECH AB (SE) | 2003-11-04 | — | — | US | disclosed |
| US-20030022913-A1 | Novel immunomodulating compounds | ACTIVE BIOTECH AB (SE) | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022913-A1 | Novel immunomodulating compounds | CD40, ICOS, CD40LG | MAPK1 1299/4885MAP2K4 1219/4885MAPKAPK3 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.