Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 6/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445584 | 1.00 | NUDT1 (0.49) | NUDT1METAP2METAP1NPY5REGFR | |
| SCHEMBL31064848 | 0.79 | SMN1; SMN2 (0.52) | NUDT1METAP2METAP1NPY5REGFR | |
| SCHEMBL375955 | 0.79 | SMN1; SMN2 (0.52) | NUDT1METAP2METAP1NPY5REGFR | |
| SCHEMBL9827151 | 0.78 | METAP2 (0.37) | NUDT1METAP2METAP1NPY5RENPP1 | |
| SCHEMBL4069549 | 0.75 | METAP2 (0.49) | METAP2METAP1NPY5REGFRLMNA | |
| SCHEMBL9121473 | 0.72 | METAP2 (0.45) | METAP2METAP1NPY5RSMN1; SMN2ENPP1 | |
| SCHEMBL4241036 | 0.72 | METAP2 (0.37) | METAP2METAP1NPY5R | |
| SCHEMBL7574497 | 0.72 | METAP2 (0.37) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL3894 | 0.71 | METAP2 (0.47) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL277596 | 0.71 | METAP2 (0.51) | METAP2METAP1NPY5REGFRENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304124-A1 | Diagnostic agent for diabetes comprising 13C labelled compound | Tokyo Gas Co., Ltd. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6509002-B1 | Carbon 13 labeled lactic acid and carrier for parenteral or oral administration; measuring radioactivity level of exhaled carbon monoxide; accurate even in light cases where subject exhibits normal blood sugar levels at time of fasting | TOKYO GAS COMPANY LIMITED (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-0913161-A2 | Diagnostic agent for diabetes | Tokyo Gas Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |