SCHEMBL3894

SCHEMBL3894

Sc1nc2ncncc2[nH]1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.47
METAP1 P53582 1/20 0.47
NPY5R Q15761 1/20 0.35
ENPP1 P22413 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11039491 0.98 METAP2 (0.50) METAP2METAP1NPY5RENPP1
Water SCHEMBL316718 0.98 METAP2 (0.46) METAP2METAP1NPY5RENPP1
SCHEMBL357003 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1
SCHEMBL277596 0.75 METAP2 (0.51) METAP2METAP1NPY5RENPP1
SCHEMBL1963575 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1
SCHEMBL375955 0.75 SMN1; SMN2 (0.52) METAP2METAP1NPY5RENPP1
SCHEMBL5632 0.75 NUDT1 (0.50) METAP2METAP1NPY5R
SCHEMBL3801779 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1
SCHEMBL2011131 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1
SCHEMBL7787137 0.75 METAP2 (0.47) METAP2METAP1NPY5RENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 115076 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
EP-3607938-B1 PHARMACEUTICAL COMPOSITION SOVIC BRKICIC LJILJANA (HR) 2026-05-27 EP claimed
EP-4747263-A1 LIPID NANOPARTICLES AND USES THEREOF University of Connecticut (US) 2026-05-27 EP claimed
CN-122075497-A Use of NLRP3 agonist for tumor treatment 2026-05-26 CN claimed
CN-116209439-B Cereblon protein modulators Saint Jude Children's Research Hospital Ltd. (US) 2026-05-26 CN claimed
WO-2026107377-A1 PHARMACOLOGICAL RE-ACTIVATION OF MUTANT PVHL KARANICOLAS JOHN (US) 2026-05-21 WO claimed
US-20260139320-A1 StarTrace: A Multiplex Drug Testing Platform for Personalized Medicine UNIV OF SOUTH CAROLINA (US) 2026-05-21 US claimed
WO-2026102563-A1 DISUBSTITUTED PYRIMIDOPYRROLE ANALOG AND USE THEREOF 深圳湾实验室坪山生物医药研发转化中心 2026-05-21 WO claimed
US-20260137700-A1 PHARMACEUTICAL COMBINATION OF PRMT5 INHIBITOR AND DNA DAMAGE-INDUCING SUBSTANCE SK BIOPHARMACEUTICALS CO LTD (KR) 2026-05-21 US claimed
WO-2026105121-A1 ANTICANCER FORMULATIONS AND USES THEREOF INTRAGEL THERAPEUTICS LTD. (IL) 2026-05-21 WO claimed
EP-0175325-A2 New 8-substituted nucleoside and purine derivatives, the process for the preparation thereof and the pharmaceutical compositions containing them Pierrel S.p.A. (IT) 1986-03-26 EP claimed
EP-0169618-A2 Method for making uniformly sized particles from water-insoluble organic compounds STERILIZATION TECHNICAL SERVICES, Inc. (US) 1986-01-29 EP claimed
EP-0120907-A1 PHARMACEUTICAL PREPARATIONS FOR USE IN ANTITUMOUR THERAPY Aston Molecules Limited (GB) 1984-10-10 EP claimed
US-4452794-A MIXTURE OF A PROSTAGLANDIN DERIVATIVE AND A CORTICOSTEROID OR A MERCAPTOPURINE ERASMUS UNIVERSITEIT ROTTERDAM (NL) 1984-06-05 US claimed
WO-1984001506-A1 PHARMACEUTICAL PREPARATIONS FOR USE IN ANTITUMOUR THERAPY UNIV BIRMINGHAM (GB) 1984-04-26 WO claimed
EP-0081882-A1 Medicine having transplant rejection and/or immunological inflammation inhibiting activities, as well as a method for inhibiting transplant rejection and/or immunological inflammation Erasmus Universiteit Rotterdam (NL) 1983-06-22 EP claimed
EP-0010964-A1 Ravidomycin, process of preparation and pharmaceutical compositions containing same AYERST, MCKENNA AND HARRISON INC. (CA) 1980-05-14 EP claimed
US-4201582-A MERCAPTO HETEROCYCLIC TONER, SILVER HALIDE, SILVER SALT OF CARBOXYALKYL HETEROCYCLIC THIONE, ORGANIC REDUCING AGNET EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4075021-A COMPOUND WHICH RELEASES A SUBSTANCE WHICH PROMOTES BLEACHING OF DEVELOPED SILVER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1978-02-21 US claimed
US-3939089-A PEROXYSULFATE TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1976-02-17 US claimed