SCHEMBL7073101

SCHEMBL7073101

Oc1cc(Cl)c(OCc2ccco2)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
ALDH1A1 P00352 4/20 0.44
LMNA P02545 4/20 0.43
POLB P06746 4/20 0.43
HPGD P15428 3/20 0.43
MAPT P10636 3/20 0.43
ALOX15 P16050 2/20 0.43
TSHR P16473 2/20 0.43
USP2 O75604 1/20 0.43
ALOX12 P18054 1/20 0.43
ATM Q13315 1/20 0.43
HSD17B10 Q99714 1/20 0.43
RAB9A P51151 2/20 0.42
TNFRSF1A P19438 1/20 0.41
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7075779 0.79 GAA (0.40) GAAALDH1A1LMNAPOLBHPGD
SCHEMBL8407890 0.72 SMN1; SMN2 (0.49) ALDH1A1LMNAPOLBHPGDMAPT
SCHEMBL8405763 0.72 LMNA (0.50) GAAALDH1A1LMNAHPGDMAPT
SCHEMBL180173 0.72 GAA (0.71) GAAALDH1A1LMNAPOLBHPGD
SCHEMBL7982345 0.71 ALDH1A1 (0.53) GAAALDH1A1POLBHPGDMAPT
SCHEMBL8405913 0.70 FABP4 (0.51) GAAALDH1A1HPGDMAPTALOX12
SCHEMBL8407186 0.70 HSD17B10 (0.44) ALDH1A1HPGDMAPTALOX15TSHR
SCHEMBL8405626 0.70 THRA (0.50) SMN1; SMN2
SCHEMBL7079251 0.70 TNFRSF1A (0.41) GAAALDH1A1LMNARAB9ATNFRSF1A
SCHEMBL8308770 0.70 GAA (0.58) GAAALDH1A1LMNAPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6589914-B2 The dihalopropene compounds of the general formula (I) have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-08 US disclosed
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2003-04-17 US disclosed
US-6376428-B1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-23 US disclosed
US-6268313-B1 CONTROLLING INSECTS, MITES, TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-31 US disclosed
US-6071861-A FOR THE CONTROL OF NOXIOUS INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, INC. (JP) 2000-06-06 US disclosed
EP-0785923-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-04-05 EP disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP disclosed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production DDT, DDC, AADAC GAA 646/4885ALDH1A1 213/4885LMNA 4375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.