Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536716 | 0.79 | HPGDS (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4924100 | 0.76 | KDM4E (0.48) | KDM4ETDP1TP53L3MBTL1SMN1; SMN2 | |
| SCHEMBL27573173 | 0.74 | GAA (0.45) | TDP1SMN1; SMN2ALOX15NPC1PKM | |
| SCHEMBL190527 | 0.74 | KDM4E (0.46) | KDM4ETDP1TP53L3MBTL1SMN1; SMN2 | |
| SCHEMBL21851670 | 0.73 | KDM4E (0.45) | KDM4ETDP1TP53L3MBTL1SMN1; SMN2 | |
| SCHEMBL13734808 | 0.71 | KDM4E (0.50) | KDM4ETDP1TP53L3MBTL1SMN1; SMN2 | |
| SCHEMBL17202963 | 0.71 | ADORA3 (0.40) | KDM4ETDP1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL5470494 | 0.71 | TRPA1 (0.46) | MEN1KMT2APOLBHPGD | |
| Dipyridyl SCHEMBL9499580 | 0.68 | KDM4E (0.52) | KDM4ETDP1TP53L3MBTL1SMN1; SMN2 | |
| SCHEMBL322756 | 0.67 | KDM4E (1.00) | KDM4ETDP1TP53L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118113-B1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA (JP) | 2013-01-30 | — | — | EP | claimed |
| CN-101611037-B | Pyridyl-triazolopyrimidine derivative or its salt, pesticide containing it and its production process | ISHIHARA SANGYO KAISHA | 2012-11-28 | — | — | CN | claimed |
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD (JP) | 2010-04-08 | — | — | US | claimed |
| CN-101611037-A | Pyridyl-triazolopyrimidine derivative or its salt, the sterilant that comprises it and its preparation method | ISHIHARA SANGYO KAISHA (JP) | 2009-12-23 | — | — | CN | claimed |
| EP-2118113-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-11-18 | — | — | EP | claimed |
| WO-2008099902-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-08-21 | — | — | WO | claimed |
| CN-107531698-B | Fused bicyclic heteroaryl derivatives having activity as PHD inhibitors | 武田药品工业株式会社 | 2024-08-13 | — | — | CN | disclosed |
| US-10287286-B2 | Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-05-14 | — | — | US | disclosed |
| US-20180072714-A1 | Novel Compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | US | disclosed |
| EP-3271357-A1 | FUSED BICYCLIC HETEROARYL DERIVATIVES HAVING ACTIVITY AS PHD INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2018-01-24 | — | — | EP | disclosed |
| WO-2016148306-A1 | FUSED BICYCLIC HETEROARYL DERIVATIVES HAVING ACTIVITY AS PHD INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-09-22 | — | — | WO | disclosed |
| EP-2118113-B1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA (JP) | 2013-01-30 | — | — | EP | disclosed |
| CN-101611037-B | Pyridyl-triazolopyrimidine derivative or its salt, pesticide containing it and its production process | ISHIHARA SANGYO KAISHA | 2012-11-28 | — | — | CN | disclosed |
| CN-101611037-A | Pyridyl-triazolopyrimidine derivative or its salt, the sterilant that comprises it and its preparation method | ISHIHARA SANGYO KAISHA (JP) | 2009-12-23 | — | — | CN | disclosed |
| CN-101611037-A | Pyridyl-triazolopyrimidine derivative or its salt, the sterilant that comprises it and its preparation method | ISHIHARA SANGYO KAISHA (JP) | 2009-12-23 | — | — | CN | disclosed |
| EP-2118113-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-11-18 | — | — | EP | disclosed |
| EP-2118113-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-11-18 | — | — | EP | disclosed |
| JP-2008222707-A | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, HARMFUL ORGANISM-CONTROLLING AGENT CONTAINING THE SAME AND METHOD FOR PRODUCING THE SAME | ISHIHARA SANGYO KAISHA LTD | 2008-09-25 | — | — | JP | disclosed |
| WO-2008099902-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008099902-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072714-A1 | Novel Compounds | F12, HAX1, C1S | KDM4E 3403/4885TDP1 3457/4885TP53 2990/4885 |
| US-10287286-B2 | Compounds | F12, C1S, F3 | KDM4E 2878/4885TDP1 3453/4885TP53 2183/4885 |
| US-20100087452-A1 | PYRIDYL-TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PESTICIDE CONTAINING IT AND ITS PRODUCTION PROCESS | SCN5A, CHRNA5, NR5A2 | KDM4E 1717/4885TDP1 2447/4885TP53 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.