Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | METAP1 | P53582 | 4/20 | 0.52 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
| ▸ | CCR8 | P51685 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | METAP2 | P50579 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzotriazole SCHEMBL28306454 | 0.86 | ALDH1A1 (0.39) | KDM4ELMNAMETAP1POLBNPC1 | |
| Benzotriazole SCHEMBL28239991 | 0.84 | ALDH1A1 (0.38) | KDM4ELMNAMETAP1POLBNPC1 | |
| Benzotriazole SCHEMBL6141636 | 0.84 | ALDH1A1 (0.38) | KDM4ELMNAMETAP1POLBNPC1 | |
| Benzotriazole SCHEMBL7048619 | 0.84 | ALDH1A1 (0.38) | KDM4ELMNAMETAP1POLBNPC1 | |
| Benzotriazole SCHEMBL29381270 | 0.84 | — | — | |
| Benzotriazole SCHEMBL6088869 | 0.84 | ALDH1A1 (0.41) | KDM4EPOLBNPC1RAB9ASMN1; SMN2 | |
| Benzotriazole SCHEMBL8956 | 0.84 | — | — | |
| Quinoxaline SCHEMBL28852776 | 0.82 | ALDH1A1 (0.37) | KDM4ELMNAMETAP1POLBNPC1 | |
| Benzotriazole SCHEMBL8477124 | 0.82 | L3MBTL1 (0.37) | KDM4ELMNAMETAP1POLBNPC1 | |
| Benzotriazole SCHEMBL9979189 | 0.82 | ALDH1A1 (0.39) | KDM4EPOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724134-B | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2022-04-01 | — | — | CN | claimed |
| CN-112724134-A | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2021-04-30 | — | — | CN | claimed |
| US-5194139-A | Antideposit agents | NIPPON MINING COMPANY LIMITED (JP) | 1993-03-16 | — | — | US | claimed |
| CN-112724134-B | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-112724134-B | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-112724134-A | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2021-04-30 | — | — | CN | disclosed |
| CN-112724134-A | Azaindazole bipyridine derivative myeloid cell proliferation inhibitor, preparation method and application thereof in pharmacy | 复旦大学 | 2021-04-30 | — | — | CN | disclosed |
| EP-0229014-B1 | MAGNETIC RECORDING MEDIUM | SONY CORPORATION (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-4735848-A | PERFLUOROALKYL ESTER LUBRICANT | SONY CORPORATION (JP) | 1988-04-05 | — | — | US | disclosed |
| EP-0229014-A2 | Magnetic recording medium | SONY CORPORATION (JP) | 1987-07-15 | — | — | EP | disclosed |